This course conveys genomics approaches to tackle the questions: "What makes us human?" and "Why are we different from each other?" Specifically, this course will introduce the state-of-the-art concepts and methodologies in human evolutionary genomics exploring topics such as human genomic variation, ancient admixture, gene-phenotype-environment interactions, adaptive developmental evolution, nature vs. nurture, genetic bases of disease, and experimental and statistical approaches to associate genotype to phenotype. The course is aimed at students in biological sciences and related fields with a strong interest in evolutionary genetics and human genomic variation. Also, this course is of relevance to advanced students in a number of disciplines, including biomedical sciences and anthropology. After taking this course, each student will have knowledge regarding the contemporary theoretical and methodological state of human evolutionary genomics.