An introductory survey of the principles and applications of optofluidics, the integration of microphotonics and microfluidics. The course covers key principles of fluid dynamics, optics and photonics and the integration of these disciplines to realize functional microsystems, with an emphasis on bioapplications. Topics covered include a survey of micro- and nano-fabrication methods, micro- and nano-fluidic principles and related transport phenomena, electromagnetic (EM) theory including light-liquid interactions. State-of-the-art optofluidic devices are treated in some detail including liquid-liquid micro-optical waveguides, fluid tunable optical micro-resonators, microfluidic lens systems and dye lasers. Nanofluids are also discussed along with optical methods for manipulating nanoparticles in fluids. Related principles of nanotechnology are also covered. This course is the same as CE 421 and course repeat rules will apply. Students should consult with their major department regarding any restrictions on their degree requirements.