2017-18
Undergraduate Degree & Course Catalog

Medicinal Chemistry (MCH)

Chemistry

363 Natural Sciences Building
North Campus
Buffalo, NY 14260-3000
Ph: 716-645-6626
F: 716-645-6963
W: chemistry.buffalo.edu
David F. Watson
Chair
Jerome Keister
Director of Undergraduate Studies
Amanda MacKellar
Undergraduate Secretary

The Learning Environment

The Chemistry program features a wide variety of class sizes, types, and delivery methods. Most General Chemistry courses consist of 3 hours of lecture per week (class sizes of ca. 360) presented by Ph. D. level faculty, in addition to 1 hour of recitation and 3 hours of laboratory (class sizes of ca. 22 students) supervised by a graduate student teaching assistant. Organic chemistry courses in the second year consist of 3 hours of lecture per week (class sizes of ca. 275) presented by Ph. D. level faculty, in addition to 1 hour of recitation and 3 hours of laboratory (class sizes of ca. 16 students) supervised by a graduate student teaching assistant. In the third and fourth year classes are generally restricted to chemistry majors. Lecture classes have enrollments of 100 to 16 and use a variety of delivery methods. Laboratory courses are low enrollment and are taught by Chemistry faculty with graduate student teaching assistants; these are heavily hands-on and with state-of-the-art instrumentation. The Department strongly encourages undergraduate research; this is conducted in the individual research groups of tenured or tenure-track faculty.

About Our Facilities

The Department of Chemistry is housed in the Natural Sciences Complex (NSC) on the North Campus. The Department occupies about 112,000 square feet of space, including 32,000 square feet for teaching laboratories and 54,000 square feet of research laboratory space. Also included are support services, such as instrumentation labs, electronic shop, stockrooms, and conference rooms.

The Chemistry Department Instrument Center maintains and operates a number of instruments that facilitate a variety of research. These include multiple mass spectrometers for analysis of ions in gas, solution and solid phases, including accurate mass confirmation. Liquid and gas chromatographs are coupled with mass spectrometry to enhance mixture analysis. Ionization techniques include electron impact, electrospray, chemical ionization, and matrix assisted laser desorption ionization. Other techniques available include FTIR, thermogravimetric analysis, scanning spectrophotometry, and differential scanning calorimetry. Nuclear Magnetic Resonance spectrometers include a Varian Gemini 300, Varian 400, 500, 600 and 750MHZ NMR for structure studies.

About Our Faculty

The staff of the Department of Chemistry includes 30 tenured or tenure-track full-time faculty (all Ph. D.), 2 full-time lecturers, 84 teaching assistants (all graduate students), and 18 support staff. Faculty members deliver lecture courses and supervise teaching assistants who are responsible for oversight of laboratory courses. The chemistry faculty includes a number of Ph.D. scientists who maintain active research programs in medicinal chemistry. Many of these have grants and contracts awarded in competitions with other scientists to support their research. The majority of outside support is from the National Institutes of Health. Faculty also hold memberships in various national organizations and several have been honored for their contributions to science.

Faculty List Directory

Please visit our department website for additional information about our faculty.

Courses


  • MCH 198SEM UB Seminar
    Seminar

    The one credit UB Seminar is focused on a big idea or challenging issue to engage students with questions of significance in a field of study and, ultimately, to connect their studies with issues of consequence in the wider world. Essential to the UB Curriculum, the Seminar helps transition to UB through an early connection to UB faculty and the undergraduate experience at a comprehensive, research university. This course is equivalent to any 198 offered in any subject. This course is a controlled enrollment (impacted) course. Students who have previously attempted the course and received a grade of F or R may not be able to repeat the course during the fall or spring semester.

    Credits: 1
    Grading: Graded (GRD)
    Typically Offered: Fall, Spring
    Other Requisites: Students who have already successfully completed the UB seminar course may not repeat this course. If you have any questions regarding enrollment for this course, please contact your academic advisor.
  • MCH 199SEM UB Seminar
    Seminar

    The three credit UB Seminar is focused on a big idea or challenging issue to engage students with questions of significance in a field of study and, ultimately, to connect their studies with issues of consequence in the wider world. Essential to the UB Curriculum, the Seminar helps students with common learning outcomes focused on fundamental expectations for critical thinking, ethical reasoning, and oral communication, and learning at a university, all within topic focused subject matter. The Seminars provide students with an early connection to UB faculty and the undergraduate experience at a comprehensive, research university. This course is equivalent to any 199 offered in any subject. This course is a controlled enrollment (impacted) course. Students who have previously attempted the course and received a grade of F or R may not be able to repeat the course during the fall or spring semester.

    Credits: 3
    Grading: Graded (GRD)
    Typically Offered: Fall, Spring
    Other Requisites: Students who have already successfully completed the first year seminar course may not repeat this course. If you have any questions regarding enrollment for this course, please contact your academic advisor.
  • MCH 300LEC Herbs and Phytomedicinals
    Lecture

    Explores sources, identification of active drugs when known, plant parts used, medicinal use, pharmacological basis of action when known, preparations used, dosage recommendations, and adverse effects and contraindications of herbs used for medicinal purposes.

    Credits: 3
    Grading: Graded (GRD)
    Typically Offered: Spring
    Prerequisites: CHE 202 Or CHE 252
  • MCH 311LEC The Chemistry of Drug Action
    Lecture

    Intended for pharmacy majors. Covers physicochemical and structural basis of drug action, drug sources, mechanisms of drug action, drug design and selectivity, drug incompatibility, and drug interactions.

    Credits: 3
    Grading: Graded (GRD)
    Typically Offered: Fall
    Prerequisites: CHE 202 Or CHE 252
  • MCH 401LEC Drug Discovery Principles
    Lecture

    Examines principles of structural, physical, and physical-organic chemistry, including mechanistic considerations involved in synthetic organic chemistry, bioorganic chemistry, and design for chemotherapeutic agents.

    Credits: 3
    Grading: Graded (GRD)
    Typically Offered: Fall
    Prerequisites: CHE 202 or CHE 252 and CHE 319 or CHE 349 and CHE 312
  • MCH 402LEC Principles of Medicinal Chemistry II
    Lecture

    Studies mechanisms of action and other factors that influence drug action within specific drug classes of pharmacodynamic and chemotherapeutic drugs, drug structures, and structure-activity relationships.

    Credits: 3
    Grading: Graded (GRD)
    Typically Offered: Spring
    Prerequisites: MCH 401
    Other Requisites: MCH 402
  • MCH 427LAB Combinatorial Chemistry
    Laboratory

    Examines medicinal and synthetic organic chemistry aspects of the design, simultaneous synthesis and computerized tracking, in a highly efficient and automated fashion of many new compounds. Students may take the lecture module alone, but the lab requires completion of the lecture and permission of the instructor.

    Credits: 2
    Grading: Graded (GRD)
    Typically Offered: Spring
  • MCH 427LEC Combinatorial Chemistry
    Lecture

    Examines medicinal and synthetic organic chemistry aspects of the design, simultaneous synthesis and computerized tracking, in a highly efficient and automated fashion of many new compounds. Students may take the lecture module alone, but the lab requires completion of the lecture and permission of the instructor.

    Credits: 1
    Grading: Graded (GRD)
    Typically Offered: Spring
  • MCH 498LAB Undergraduate Research Participation in Medicinal Chemistry
    Laboratory

    Involves projects in medicinal chemistry involving a literature search and lab work.

    Credits: 1 - 6
    Grading: Graded (GRD)
    Typically Offered: Fall, Spring
  • MCH 499TUT Independent Studies
    Tutorial

    Involves development of a special topic of student interest under a tutorial arrangement.

    Credits: 1 - 6
    Grading: Graded (GRD)
    Typically Offered: Fall, Spring, Summer

Chemistry

363 Natural Sciences Building
North Campus
Buffalo, NY 14260-3000
Ph: 716-645-6626
F: 716-645-6963
W: chemistry.buffalo.edu
David F. Watson
Chair
Jerome Keister
Director of Undergraduate Studies
Amanda MacKellar
Undergraduate Secretary
Published: May 04, 2017 11:49:10 AM